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Alternative Factors in Possible Involvement of Coronary Microvascular Dysfunction in Older Patients with HFpEF.


ABSTRACT: Objectives: Coronary microvascular dysfunction (CMD) is associated with many heart diseases, including heart failure (HF) with preserved ejection fraction (HFpEF). Invasive examinations for CMD detection are difficult in older patients with HFpEF, and the decision criteria for noninvasive CMD measurements are unclear. We aimed to identify alternative factors in the possible involvement of CMD in the progression and prognosis of HFpEF. Methods: We analyzed 607 patients with HFpEF who were hospitalized for acute decompensated HF without a history of coronary artery disease (CAD). Blood tests and transthoracic echocardiography were performed. We focused on left ventricular hypertrophy (LVH) and coronary perfusion pressure (diastolic blood pressure, dBP). Results: The pati

SUBMITTER: Hoshida S 

PROVIDER: S-EPMC11477810 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature