Skin Barrier Function and Microtopography in Patients with Atopic Dermatitis.

ABSTRACT: Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease whose incidence is increasing. Skin barrier dysfunction plays an important role in this disease. It has been observed that AD patients have higher transepidermal water loss (TEWL) and lower stratum corneum hydration (SCH); however, there is little information about skin microtopography in this pathology. The objective of this study is to evaluate skin barrier dysfunction and structural changes in patients with AD. Methods: A cross-sectional study was conducted including patients with AD. Parameters of skin barrier function were measured (TEWL, temperature, erythema, pH, skin hydration, elasticity) and also other topographical parameters (scaliness, wrinkles, smoothness, surface, contrast, variance) in b

SUBMITTER: Pretel-Lara C 

PROVIDER: S-EPMC11477937 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature