Inflammation in Older Poles with Localized and Widespread Chronic Pain-Results from a Population-Based PolSenior Study.

ABSTRACT: Background: Inflammation leads to a decrease in the excitation threshold and the sensitization of peripheral nociceptors. However, little is known about the effect of inflammation on the sensing of regional (CRegP) and widespread chronic pain (CWP) in older adults. This analysis aimed to characterize the prevalence and associates of both types of chronic pain in a population-based cohort. Methods: Our analysis was based on the Polish nationwide PolSenior study database. We excluded participants with moderate-to-severe dementia. Respondents answered questions concerning the occurrence of pain in 10 regions. CWP was defined as chronic pain present in the axial region (neck, upper back, lower back) and any part of both the lower (lower leg, hip, knee, foot) and upper (shoulder,

SUBMITTER: Chudek A 

PROVIDER: S-EPMC11478211 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature