Preparation of Antimicrobial Agents: From Interpolyelectrolyte Complexes to Silver-Containing Metal-Polymer Complexes and Nanocomposites.

ABSTRACT: In order to control pathogenic microorganisms, three polymer compositions were prepared and tested. First, a water-soluble positively charged polycomplex was synthesized via the electrostatic binding of anionic polyacrylic acid to an excess of polyethylenimine to enhance the biocidal activity of the polycation. Second, an aqueous solution of AgNO₃ was added to the polycomplex, thus forming a ternary polycation-polyanion-Ag¹⁺ complex with an additional antimicrobial effect. Third, the resulting ternary complex was subjected to UV irradiation, which ensured the conversion of Ag¹⁺ ions into Ag nanoparticles ranging in size mainly from 10 to 20 nm. Aqueous solutions of the polymer compositions were added to suspensions of the Gram-positive bacteria S. aureus

SUBMITTER: Klimov DI 

PROVIDER: S-EPMC11478344 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature