Association of Serum Bile Acid Profile with Diet and Physical Activity Habits in Japanese Middle-Aged Men.

ABSTRACT:

Background/objectives

Circulating bile acid (BA) profiles change with lifestyle and are closely related to intestinal BA metabolisms such as deconjugation and conversion to secondary BAs. The composition of BA in the blood is involved in systemic nutrient metabolism and intestinal health. Herein, we explored the associations of lifestyle and physical fitness with the circulating BA profile of middle-aged men.

Methods

Data of 147 male participants (aged 50-64 years; BMI < 26 kg/m²; no medication for diabetes or dyslipidemia) from the Japan Multi-Institutional Collaborative Cohort study were analyzed. Serum concentrations of 15 types of BAs were examined for associations with variables on dietary habits, physical-activity habits, and physical fitness.

Results

SUBMITTER: Aoi W 

PROVIDER: S-EPMC11478694 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature