Relationship between albumin and rheumatoid arthritis: Evidence from NHANES and Mendelian randomization.

ABSTRACT: With the rising incidence of rheumatoid arthritis (RA) and the increasing percentage of serum RF negativity, more and more accurate methods are urgently needed for the early diagnosis and prevention of RA, among which serum albumin (ALB) is closely related to the development of RA, and it is expected to become a new auxiliary diagnostic means, but its relationship with RA is not clear, so the present study aimed to investigate the Causal relationship. In this study, we used a generalized linear model and smoothed curve fitting to comprehensively evaluate the relationship between ALB and RA through the data of ALB and RA in the NHANES database, in addition, we further used inverse variance weighted (IVW) in Mendelian randomization (MR) in conjunction with the other 4 methods to further vali

SUBMITTER: Liu K 

PROVIDER: S-EPMC11479416 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature