Association of triglyceride-glucose index with diabetes or prediabetes in Chinese hypertensive patients: A retrospective cohort study.

ABSTRACT: Insulin resistance is a key factor in diabetes development. This study aimed to investigate the association between baseline triglyceride-glucose (TyG) index, a surrogate marker of insulin resistance, and the onset of hyperglycemia in Chinese individuals with hypertension. Using the Rich Healthcare Group database, this retrospective cohort study included 28,687 hypertensive individuals without preexisting diabetes. A wide range of demographic information and baseline biochemical indicators was collected and rigorously analyzed. This study utilized the Cox proportional hazards model and smooth curve fitting to explore the link between TyG index and the risk of developing hyperglycemia. The robustness of the findings was validated by sensitivity and subgroup analyses. During longitudinal mon

SUBMITTER: Wu J 

PROVIDER: S-EPMC11479436 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature