Metabolomics and proteomics in occupational medicine: a comprehensive systematic review.

ABSTRACT:

Background

Occupational biomonitoring is essential for assessing health risks linked to workplace exposures. The use of 'omics' technologies, such as metabolomics and proteomics, has become crucial in detecting subtle biological alterations induced by occupational hazards, thereby opening novel avenues for biomarker discovery.

Aims

This systematic review aims to evaluate the application of metabolomics and proteomics in occupational health.

Methods

Following the PRISMA guidelines, we conducted a comprehensive search on PubMed, Scopus, and Web of Science for original human studies that use metabolomics or proteomics to assess occupational exposure biomarkers. The risk of bias was assessed by adapting the Cochrane Collaboration tool and the Newcastle-Ottawa Quality Asse

SUBMITTER: Ochoa-Leite C 

PROVIDER: S-EPMC11479568 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature