Clonal and resistance profiles of fluoroquinolone-resistant uropathogenic <i>Escherichia coli</i> in countries with different practices of antibiotic prescription.

ABSTRACT:

Background

Antibiotic prescription practices differ between countries, influencing regional antimicrobial resistance prevalence. However, comparisons of clonal diversity among resistant bacteria in countries with different prescribing practices are rare. The rise of fluoroquinolone-resistant Escherichia coli (FQREC), often multidrug-resistant, exacerbates global antibiotic resistance. Unlike in the USA, antibiotics are commonly dispensed in Iraq without prescriptions, leading to widespread overuse and misuse. This study aimed to assess the impact of varying antibiotic use practices on FQREC diversity.

Methods

We compared FQREC prevalence, multidrug resistance, and clonality of FQREC among E. coli isolated from urine submitted between 2017 and 2018 to three US h

SUBMITTER: Choudhury D 

PROVIDER: S-EPMC11479919 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature