Impact of mini-dose dexmedetomidine supplemented analgesia on sleep structure in patients at high risk of obstructive sleep apnea: a pilot trial.

ABSTRACT:

Background

Obstructive sleep apnea (OSA) is common in surgical patients and associated with worse perioperative outcomes.

Objectives

To investigate the effect of mini-dose dexmedetomidine supplemented analgesia on postoperative sleep quality pattern in patients at high risk of OSA.

Design

A pilot randomized, double-blind, placebo-controlled trial.

Setting

A tertiary university hospital in Beijing, China.

Patients

One hundred and fifty-two adult patients who had a STOP-Bang score ≥3 and a serum bicarbonate level ≥28 mmol/L and were scheduled for major noncardiac surgery between 29 January 2021 and 20 September 2022.

Intervention

After surgery, patients were provided with high-flow nasal cannula and randomized in a 1:1 ratio to receive self-controll

SUBMITTER: Sun P 

PROVIDER: S-EPMC11480026 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature