Association between uric acid and the risk of depressive symptoms in US adults: results from NHANES 2005-2018.

ABSTRACT:

Background

This study explores the relationship between serum uric acid(UA) levels and depression. UA is the final product of purine metabolism in the human body, possessing certain physiological functions such as blood pressure regulation, antioxidation, DNA protection, and anti-aging, thereby drawing attention for its potential role in preventing and treating depression.

Methods

This cross-sectional study includes 32,424 participants aged ≥ 20 years from the National Health and Nutrition Examination Survey (NHANES) conducted between 2005 and 2018, generating a nationally representative database. Depressive symptoms were assessed using the Patient Health Questionnaire-9. Serum uric acid concentration was measured using the uricase-peroxidase coupled method, and participants

SUBMITTER: Wang J 

PROVIDER: S-EPMC11480327 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature