Risk of infections among persons treated with opioids for chronic pain: a systematic review and meta-analysis protocol.

ABSTRACT:

Introduction

Millions of persons with chronic pain across North America and Europe use opioids. While the immunosuppressive properties of opioids are associated with risks of infections, these outcomes could be mitigated through careful patient selection and monitoring practices when appropriate. It is important to recognise that some patients do benefit from a carefully tailored opioid therapy. Enough primary studies have been published to date regarding the role of opioids in potential immunosuppression presenting as an increased rate of infection acquisition, infectious complications and mortality. There is thus a critical need for a consensus in this area.

Methods and analysis

The methodology is based on the Preferred Reporting Items for Systematic Reviews and Meta-Analy

SUBMITTER: Kudrina I 

PROVIDER: S-EPMC11481125 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature