Effect of calcium channel blockers on influenza incidence: a population-based retrospective cohort study using administrative claims data in Japan.

ABSTRACT:

Objectives

Laboratory experiments have indicated that calcium channel blockers (CCBs) inhibit the entry and replication of influenza A virus in cells. However, no clinical studies have assessed the incidence of influenza among patients receiving CCBs. This study aimed to investigate the association between CCB use and the incidence of influenza among patients with hypertension using administrative claims data in Japan.

Design

Retrospective cohort study.

Setting

Administrative health insurance claims database of Kumamoto Prefecture, Japan.

Participants

360 515 patients with hypertension (10th edition of the International Classification of Diseases code I10) who were prescribed CCBs and 171 142 patients who were prescribed angiotensin-converting enzyme inhibitors

SUBMITTER: Imai T 

PROVIDER: S-EPMC11481128 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature