Influence of procedural timing on the preventive yield of percutaneous patent foramen ovale closure.

ABSTRACT:

Background

The benefit of patent foramen ovale closure (PFOC) ≤9 months after a cryptogenic stroke has been demonstrated in several randomised clinical trials. There is, however, insufficient data to support PFOC in non-recent cryptogenic strokes.

Aims

The objective of the study was to evaluate the effectiveness of PFOC in relation to the time since the patient's most recent cryptogenic cerebrovascular event (CVE) or systemic embolism (SE).

Methods

We conducted a multicentre, retrospective cohort study with international participation, to assess the results of an early closure (EC, <9 months) for secondary prevention versus a delayed closure (DC, ≥9 months). Recurrence of CVE/SE following PFOC was evaluated as the primary endpoint.

Results

496 patients were inc

SUBMITTER: Jeronimo A 

PROVIDER: S-EPMC11481237 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature