Minimally Invasive Injectable Gel for Local Immunotherapy of Liver and Gastric Cancer.

ABSTRACT: Local immunotherapy represents a promising solution for preventing tumor recurrence and metastasis post tumor surgical resection by eliminating residue tumor cells as well as eliciting tumor-specific immune responses. Minimally invasive surgery has become a mainstream surgical method worldwide due to its advantages of aesthetics and rapid postoperative recovery. Unfortunately, the currently reported local immunotherapy strategies are mostly designed to be used after open laparotomy, which go against the current surgical philosophy of minimally invasive therapy and is not suitable for clinical translation. Aiming at this problem, a minimally invasive injectable gel (MIGel) is herein reported loaded with immunotherapeutic agents for gastric and liver cancer postoperative treatment. The MIGel

SUBMITTER: Si X 

PROVIDER: S-EPMC11481255 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature