Detailed analysis of electrogram peak frequency to guide ventricular tachycardia substrate mapping.

ABSTRACT:

Aims

Differentiating near-field (NF) and far-field (FF) electrograms (EGMs) is crucial in identifying critical arrhythmogenic substrate during ventricular tachycardia (VT) ablation. A novel algorithm annotates NF-fractionated signals enabling EGM peak frequency (PF) determination using wavelet transformation. This study evaluated the algorithms' effectiveness in identifying critical components of the VT circuit during substrate mapping.

Methods and results

A multicentre, international cohort undergoing VT ablation was investigated. VT activation maps were used to demarcate the isthmus zone (IZ). Offline analysis was performed to evaluate the diagnostic performance of low-voltage area (LVA) PF substrate mapping. A total of 30 patients encompassing 198 935 EGMs were included.

SUBMITTER: Mayer J 

PROVIDER: S-EPMC11481296 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature