Melatonin levels and embryo quality in IVF patients with diminished ovarian reserve: a comparative study.

ABSTRACT:

Background

Melatonin, a hormone found in various bodily fluids and cells, is known for its potent antioxidative, anti-apoptotic, and endocrine regulatory properties. This study aimed to analyze melatonin levels in patients with diminished ovarian reserve (DOR) and its impact on embryo quality.

Methods

We enrolled 85 women who were undergoing in vitro fertilization or intracytoplasmic sperm injection procedures, including normal ovarian reserve (NOR, n = 27), pathological DOR (DOR-Path, n = 25), and physiological DOR (DOR-Phy, n = 33). Melatonin levels in patient serum and follicular fluid were assessed using ELISA, and correlations between melatonin levels and indicators of embryo quality were examined.

Results

Our findings indicate that melatonin levels in the follic

SUBMITTER: Wang Y 

PROVIDER: S-EPMC11481365 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature