The impact of physical activity on progression-free and overall survival in metastatic breast cancer based on molecular subtype.

ABSTRACT:

Background

Although adequate physical activity has been shown to be beneficial in early breast cancer, evidence in metastatic breast cancer is sparse and contradictory, which could be related to distinct effects of physical activity on the different molecular cancer subtypes. Therefore, we here evaluated the effect of physical activity on progression-free and overall survival (PFS, OS) in metastatic breast cancer, specifically looking at molecular subtypes.

Methods

International Physical Activity Questionnaire (IPAQ) questionnaires, filled out by patients enrolled in the prospective PRAEGNANT registry (NCT02338167; n = 1,270) were used to calculate metabolic equivalent task (MET) minutes, which were subsequently categorized into low (n = 138), moderate (n = 995) or high IPAQ

SUBMITTER: Ziegler P 

PROVIDER: S-EPMC11481816 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature