Microscope integrated MHz optical coherence tomography system for neurosurgery: development and clinical in-vivo imaging.

ABSTRACT: Neurosurgical interventions on the brain are impeded by the requirement to keep damages to healthy tissue at a minimum. A new contrast channel enhancing the visual separation of malign tissue should be created. A commercially available surgical microscope was modified with adaptation optics adapting the MHz speed optical coherence tomography (OCT) imaging system developed in our group. This required the design of a scanner optics and beam delivery system overcoming constraints posed by the mechanical and optical parameters of the microscope. High quality volumetric OCT C-scans with dense sample spacing can be acquired in-vivo as part of surgical procedures within seconds and are immediately available for post-processing.

SUBMITTER: Draxinger W 

PROVIDER: S-EPMC11482179 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature