Association of Anxiety with Uncinate Fasciculus Lesion Burden in Multiple Sclerosis.

ABSTRACT:

Importance

Multiple sclerosis (MS) is an immune-mediated neurological disorder that affects 2.4 million people world-wide, and up to 60% experience anxiety.

Objective

We investigated how anxiety in MS is associated with white matter lesion burden in the uncinate fasciculus (UF).

Design

Retrospective case-control study of participants who received research-quality 3-tesla (3T) neuroimaging as part of MS clinical care from 2010-2018. Analyses were performed from June 1^st to September 30^th, 2024.

Setting

Single-center academic medical specialty MS clinic.

Participants

Participants were identified from the electronic medical record. All participants were diagnosed by an MS specialist and completed research-quality MRI at 3T. After exclu

SUBMITTER: Baller EB 

PROVIDER: S-EPMC11482984 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature