Effect of Ventilator Mode on Ventilator-Free Days in Critically Ill Adults: A Randomized Trial.

ABSTRACT:

Rationale

For critically ill adults receiving invasive mechanical ventilation, the ventilator mode determines how breaths are delivered. Whether the choice of ventilator mode affects outcomes for critically ill patients is unknown. To compare the effects of three common ventilator modes (volume control, pressure control, and adaptive pressure control) on death and duration of mechanical ventilation.

Methods

We conducted a pragmatic, cluster-randomized, crossover trial among adults receiving invasive mechanical ventilation in a medical ICU between November 1, 2022 and July 31, 2023. Each month, patients in the participating unit were assigned to receive volume control, pressure control, or adaptive pressure control during continuous mandatory ventilation. The primary outcome

SUBMITTER: Seitz KP 

PROVIDER: S-EPMC11483002 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature