The predictive performance of the ANCA renal risk score in patients over 65 years of age with renal ANCA-associated vasculitis.

ABSTRACT:

Background

The anti-neutrophil cytoplasmic antibody (ANCA) renal risk score (ARRS) for predicting renal survival in ANCA-associated vasculitis (AAV) had not previously been validated in adults over 65 years of age and presenting impairments associated with an aging kidney, a high cardiovascular comorbidity burden and prevalent microscopic polyangiitis.

Methods

We retrospectively studied a cohort of 192 patients over 65 years of age [median (interquartile range) age: 73 (68-78) years], including 17.2% with renal-limited vasculitis, 49.5% with microscopic polyangiitis and 33.3% with granulomatosis with polyangiitis, at six centres in northern France. The primary study endpoint was the cumulative incidence of end-stage kidney disease (ESKD, maintenance of dialysis for at least

SUBMITTER: de Berny Q 

PROVIDER: S-EPMC11483564 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature