Urine cotinine versus self-reported smoking and the risk of chronic kidney disease.

ABSTRACT:

Background and hypothesis

Evidence on the role of smoking in the development of chronic kidney disease (CKD) has mostly relied on self-reported smoking status. We aimed to compare the associations of smoking status as assessed by self-reports and urine cotinine with CKD risk.

Methods

Using the PREVEND prospective study, smoking status was assessed at baseline using self-reports and urine cotinine in 4333 participants (mean age, 52 years) without a history of CKD at baseline. Participants were classified as never, former, light current, and heavy current smokers according to self-reports and comparable cutoffs for urine cotinine. Hazard ratios (HRs) with 95% confidence intervals (CIs) were estimated for CKD.

Results

The percentages of self-reported and cotinine-assesse

SUBMITTER: Kunutsor SK 

PROVIDER: S-EPMC11483611 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature