A study investigating how the albumin-globulin ratio relates to depression risk within U.S. adults: a cross-sectional analysis.

ABSTRACT:

Background

The relationship between the albumin-to-globulin ratio (AGR) and depression is not well understood. This analysis aims to investigate the relationship between AGR in conjunction with depression in U.S. adults.

Methods

This study analyzed information from 31,363 individuals collected by NHANES during the years 2005 to 2018. The PHQ-9 scale was employed to gauge depression, where a score of 10 or above signified depression. Weighted multivariable logistic modeling along with smooth curve fitting were applied to explore the AGR-depression connection. To confirm our findings, we carried out sensitivity analyses, subgroup analyses, and interaction tests.

Results

After adjusting for confounding variables, a higher AGR is associated with a lower risk of depression

SUBMITTER: Xu Q 

PROVIDER: S-EPMC11484099 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature