Antitumour activity of oleanolic acid: A systematic review and meta‑analysis.

ABSTRACT: Oleanolic acid (OA), a compound known for its potent antitumour properties, has been the subject of investigations in both cell and animal models. Although OA has good biological activity, its low water solubility and bioavailability limit its therapeutic use, and therefore translating the potential of OA into the clinical oncology setting remains challenging. The present systematic review and meta-analysis utilized evidence from animal model studies to gain insights into the antitumour mechanisms of OA to address the gap in understanding, and to provide guidance for future research directions and potential clinical applications. The guidelines outlined in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses were applied in the present study and a comprehensive search was

SUBMITTER: Zeng Y 

PROVIDER: S-EPMC11484195 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature