Genomic analysis of <i>Brucella</i> isolates from animals and humans, Turkiye, 2010 to 2020.

ABSTRACT: BackgroundBrucellosis is a bacterial zoonosis causing severe illness in humans and animals and leading to economic losses in the livestock production in Türkiye and other endemic countries.AimWe aimed at investigating genomic differences of Brucella isolates from animals and humans in Türkiye.MethodsWe used whole genome sequencing (WGS) to assess the genetic diversity of Brucella isolates from 41 provinces in Türkiye and compared with isolates from other countries. We applied allele-based typing and core genome single nucleotide polymorphism (cgSNP) determination.ResultsOf the 106 Turkish Brucella isolates included, 57 were B. abortus and 49 were B. melitensis. One B. melitensis and two B. abortus isolates were identified as vaccine strains.

SUBMITTER: Akar K 

PROVIDER: S-EPMC11484290 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature