Recurrence and Risk Factors of Giant Cell Tumors in Hand Bones: A Systematic Review.

ABSTRACT:

Background

Giant cell tumor of bone (GCTB) is a locally aggressive tumor that may affect the bones of the hand and rarely causes pulmonary metastasis. It exhibits a variable recurrence rate after surgical interventions, which presents challenges in its management. This systematic review aims to delineate recurrence rates and identify risk factors for GCTB in the hand.

Methods

We conducted a systematic literature search in April 2024, following PRISMA guidelines, on PubMed and TDNet for studies reporting postsurgical recurrence of GCTB in the hand. Cohort and case-control studies provided recurrence rates, whereas case reports and series were utilized to identify risk factors, compensating for the sparse data in the primary studies. We used descriptive statistics, χ²

SUBMITTER: Berger O 

PROVIDER: S-EPMC11484632 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature