Association between fruit intake and non-small cell lung cancer: a Mendelian randomization study.

ABSTRACT:

Background

Several studies have explored the potential relationship between fruit consumption and non-small cell lung cancer (NSCLC). However, the impact of dried fruit on NSCLC risk remains unclear. Additionally, the presence of confounding variables in these observational investigations could not be avoided. Therefore, the aim of this article was to explore the potential relationship between fruits intake and NSCLC.

Methods

We extracted fruit intake data from the UK Biobank and utilized a genome-wide association study (GWAS) encompassing 218,792 individuals for NSCLC data. We employed a two-sample Mendelian randomization (MR) analysis to investigate the potential causal associations between fruit intake and the risk of NSCLC. The major method of analysis was the inverse va

SUBMITTER: Pan C 

PROVIDER: S-EPMC11484710 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature