Post-diagnosis smoking habit change and incident dementia in cancer survivors.

ABSTRACT:

Introduction

Many individuals change their smoking habits after cancer diagnosis. We aimed to evaluate the association of post-diagnosis smoking habit change with incident dementia in cancer survivors.

Methods

We identified 558,127 individuals who were diagnosed with cancer at age ≥ 20 and survived for ≥ 3 years. Participants were classified into four groups: (1) sustained non-smokers, (2) initiators/relapsers, (3) quitters, and (4) continuing smokers. Dementia risk in each group was assessed using a cause-specific Cox model.

Results

After cancer diagnosis, 2.3% of pre-diagnosis non-smokers initiated/relapsed into smoking, while 51.7% of pre-diagnosis smokers quit smoking. Compared to sustained non-smokers, multivariable-adjusted risk of dementia was 29% higher among

SUBMITTER: Lee HH 

PROVIDER: S-EPMC11485076 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature