Effect of trabecular architectures on the mechanical response in osteoporotic and healthy human bone.

ABSTRACT: Research at the mesoscale bone trabeculae arrangement yields intriguing results that, due to their clinical resolution, can be applied in clinical field, contributing significantly to the diagnosis of bone-related diseases. While the literature offers quantitative morphometric parameters for a thorough characterization of the mesoscale bone network, there is a gap in understanding relationships among them, particularly in the context of various bone pathologies. This research aims to bridge these gaps by offering a quantitative evaluation of the interplay among morphometric parameters and mechanical response at mesoscale in osteoporotic and non-osteoporotic bones. Bone mechanical response, dependent on trabecular arrangement, is defined by apparent stiffness, computationally calculated usi

SUBMITTER: Bregoli C 

PROVIDER: S-EPMC11485120 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature