A new map of the rat isocortex and proisocortex: cytoarchitecture and M₂ receptor distribution patterns.

ABSTRACT: Neurotransmitters and their receptors are key molecules in information transfer between neurons, thus enabling inter-areal communication. Therefore, multimodal atlases integrating the brain's cyto- and receptor architecture constitute crucial tools to understand the relationship between its structural and functional segregation. Cholinergic muscarinic M₂ receptors have been shown to be an evolutionarily conserved molecular marker of primary sensory areas in the mammalian brain. To complement existing rodent atlases, we applied a silver cell body staining and quantitative in vitro receptor autoradiographic visualization of M₂ receptors to alternating sections throughout the entire brain of five adult male Wistar rats (three sectioned coronally, one horizontally, one sa

SUBMITTER: Haghir H 

PROVIDER: S-EPMC11485150 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature