Inflammatory eye disease is a risk factor for future microscopic colitis: A nationwide population-based matched case control study.

ABSTRACT:

Background

Microscopic colitis (MC) is an inflammatory disorder of the colon. To date, the relationship between inflammatory eye diseases and MC is unclear.

Objective

To assess whether inflammatory eye disease (iridocyclitis and episcleritis) is a risk factor for MC.

Methods

We conducted a nationwide matched case control study in Sweden leveraging the ESPRESSO-study (a Swedish database containing data on all biopsies from the gastrointestinal tract from 1965 to 2017). In total, we identified 14,338 patients with biopsy-verified MC (diagnosed from 1981 to 2017). Patients with MC were matched (by age, sex, county and year of birth) with 68,753 controls from the general population and the occurrence of preceding inflammatory eye diseases (defined as diagnosis of episcler

SUBMITTER: Bergman D 

PROVIDER: S-EPMC11485298 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature