Quantitative assessment of renal steatosis in patients with type 2 diabetes mellitus using the iterative decomposition of water and fat with echo asymmetry and least squares estimation quantification sequence imaging: repeatability and clinical implications.

ABSTRACT:

Background

Fatty kidney disease is linked to renal function damage, but there is no noninvasive tool for monitoring renal fat accumulation. This study aimed to explore the repeatability of the iterative decomposition of water and fat with echo asymmetry and least squares estimation quantification (IDEAL-IQ) sequence imaging in quantifying renal fat deposition and to assess the differences observed in patients with type 2 diabetes mellitus (T2DM).

Methods

A total of 26 healthy participants underwent two IDEAL-IQ scans without repositioning, and the repeatability of the imaging technique was assessed with Bland-Altman analysis. Additionally, 96 patients with T2DM underwent a single IDEAL-IQ scan for the examination of renal fat deposition. The patients with T2DM were classifie

SUBMITTER: Liu J 

PROVIDER: S-EPMC11485345 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature