Horizontal cortical connections shape intrinsic traveling waves into feature-selective motifs that regulate perceptual sensitivity.

ABSTRACT: Intrinsic cortical activity forms traveling waves that modulate sensory-evoked responses and perceptual sensitivity. These intrinsic traveling waves (iTWs) may arise from the coordination of synaptic activity through long-range feature-dependent horizontal connectivity within cortical areas. In a spiking network model that incorporates feature-selective patchy connections, we observe iTW motifs that result from shifts in excitatory/inhibitory balance as action potentials traverse these patchy connections. To test whether feature-selective motifs occur in vivo, we examined data recorded in the middle temporal visual area (Area MT) of marmosets performing a visual detection task. We find that some iTWs form motifs that are feature selective, exhibiting direction-selective modulations in spik

SUBMITTER: Davis ZW 

PROVIDER: S-EPMC11485754 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature