RNAtango: Analysing and comparing RNA 3D structures via torsional angles.

ABSTRACT: RNA molecules, essential for viruses and living organisms, derive their pivotal functions from intricate 3D structures. To understand these structures, one can analyze torsion and pseudo-torsion angles, which describe rotations around bonds, whether real or virtual, thus capturing the RNA conformational flexibility. Such an analysis has been made possible by RNAtango, a web server introduced in this paper, that provides a trigonometric perspective on RNA 3D structures, giving insights into the variability of examined models and their alignment with reference targets. RNAtango offers comprehensive tools for calculating torsion and pseudo-torsion angles, generating angle statistics, comparing RNA structures based on backbone torsions, and assessing local and global structural similarities us

SUBMITTER: Mackowiak M 

PROVIDER: S-EPMC11486365 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature