A metabolic modeling-based framework for predicting trophic dependencies in native rhizobiomes of crop plants.

ABSTRACT: The exchange of metabolites (i.e., metabolic interactions) between bacteria in the rhizosphere determines various plant-associated functions. Systematically understanding the metabolic interactions in the rhizosphere, as well as in other types of microbial communities, would open the door to the optimization of specific predefined functions of interest, and therefore to the harnessing of the functionality of various types of microbiomes. However, mechanistic knowledge regarding the gathering and interpretation of these interactions is limited. Here, we present a framework utilizing genomics and constraint-based modeling approaches, aiming to interpret the hierarchical trophic interactions in the soil environment. 243 genome scale metabolic models of bacteria associated with a specific dise

SUBMITTER: Ginatt AA 

PROVIDER: S-EPMC11486489 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature