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Atrial Fibrillation and Semaglutide Effects in Obesity-Related Heart Failure With Preserved Ejection Fraction: STEP-HFpEF Program.


ABSTRACT:

SUBMITTER: Verma S 

PROVIDER: S-EPMC11486552 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature

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Atrial Fibrillation and Semaglutide Effects in Obesity-Related Heart Failure With Preserved Ejection Fraction: STEP-HFpEF Program.

Verma Subodh S   Butler Javed J   Borlaug Barry A BA   Davies Melanie J MJ   Kitzman Dalane W DW   Petrie Mark C MC   Shah Sanjiv J SJ   Jensen Thomas Jon TJ   Rasmussen Søren S   Rönnbäck Cecilia C   Merkely Bela B   O'Keefe Evan E   Kosiborod Mikhail N MN  

Journal of the American College of Cardiology 20240830 17


<h4>Background</h4>Obesity is a key factor in the development and progression of both heart failure with preserved ejection fraction (HFpEF) and atrial fibrillation (AF). In the STEP-HFpEF Program (comprising the STEP-HFpEF [Research Study to Investigate How Well Semaglutide Works in People Living With Heart Failure and Obesity] and STEP-HFpEF DM [Research Study to Look at How Well Semaglutide Works in People Living With Heart Failure, Obesity and Type 2 Diabetes] trials), once-weekly semaglutid  ...[more]

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