Automated liquid-liquid deep eutectic solvents based microextraction procedure for determination of acrylamide in foodstuffs by high-performance liquid chromatography with ultraviolet detection.

ABSTRACT: For the rapid and efficient determination of acrylamide in food products by HPLC-UV, an environmentally friendly analytical approach has been developed, including liquid-phase extraction and subsequent liquid-liquid microextraction using a deep eutectic solvent. To automate the procedure, the flow-through "lab in a syringe" method was used. Acrylamide is considered a potential endocrine disrupting chemical and its main source is fried foods, which are widely consumed by both children and adults. To extract and concentrate acrylamide, hydrophobic deep-eutectic solvents based on various carboxylic acids and natural terpenoids were studied for the first time. It was found that benzoic acid, as a precursor of the extraction solvent, promotes the transfer of hydrophilic acrylamide from the aque

SUBMITTER: Shishov A 

PROVIDER: S-EPMC11486872 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature