Stem cell therapy for COVID-19 treatment: An umbrella review.

ABSTRACT:

Background

COVID-19 has presented significant obstacles to healthcare. Stem cell therapy, particularly mesenchymal stem cells (MSCs), has emerged as a potential treatment modality due to its immunomodulatory and regenerative properties. This umbrella review aims to synthesize current evidence from systematic reviews on the safety and efficacy of stem cell therapy in COVID-19 treatment.

Methods

A thorough literature search was performed across Embase, PubMed, Cochrane and Web of Science from December 2019 to February 2024. Systematic reviews focusing on the use of stem cell therapy for COVID-19 were included. Evidence was synthesized by meta-analysis using R software (V 4.3) for each outcome. The certainty of evidence was assessed using the GRADE approach.

Results

A to

SUBMITTER: Tang C 

PROVIDER: S-EPMC11487013 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature