Transcatheter tricuspid valve intervention versus medical therapy for symptomatic tricuspid regurgitation: a meta-analysis of reconstructed time-to-event data.

ABSTRACT:

Background

Transcatheter tricuspid valve intervention (TTVI) has demonstrated safety and efficacy in treating high-risk patients with tricuspid regurgitation (TR). The authors aimed to perform a meta-analysis based on reconstructed time-to-event data to compare the clinical benefit of TTVI with medical therapy (MED).

Methods

A systematic literature search was conducted in major databases, including PubMed, Embase, and the Cochrane Library, until 20 October 2023. All studies comparing the outcomes between TTVI and MED were included. The primary outcome was all-cause mortality. The secondary outcomes included heart failure (HF) hospitalization and the composite outcome of all-cause mortality and HF hospitalization.

Results

Five studies covering 3826 patients (1146 recei

SUBMITTER: Fu G 

PROVIDER: S-EPMC11487027 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature