Correlation of Lymph Node Characteristics and Extranodal Extension in Oral Cavity Squamous Cell Carcinoma.

ABSTRACT:

Objective

Identify correlations between lymph node characteristics and extranodal extension (ENE).

Study design

Retrospective chart review.

Setting

Tertiary care center.

Methods

Patients who underwent neck dissection for oral cavity squamous cell carcinoma from 2004 to 2018 were included, with a starting sample of 496. The primary outcome was ENE in at least 1 lymph node. Additional variables included number of dissected nodes, positive nodes by level, positive lymph node ratio (LNR), and diameter of metastatic deposit and ENE focus. Univariate and multivariate binary logistic regression analyses were performed to determine correlations between included variables and ENE.

Results

Of the 496 patients, 233 had nodal metastasis (47.0%). 13,814 nodes were re

SUBMITTER: Wenzel PA 

PROVIDER: S-EPMC11487070 | biostudies-literature | 2024 Oct-Dec

REPOSITORIES: biostudies-literature