Head-to-Head Comparison Between ¹⁸F-FDG PET and Leukocyte Scintigraphy to Monitor Treatment Responses in Necrotizing Otitis Externa.

ABSTRACT:

Background

Necrotizing otitis externa (NOE) is a rare disease associated with high morbidity and mortality, and there is currently no available accurate biomarker to assess treatment responses. The aim of the current study was to evaluate and directly compare the diagnostic performances of 18-Fluoro-deoxyglucose positron emission tomography (¹⁸F-FDG PET) and labeled leukocyte scintigraphy (LS) to monitor treatment responses in NOE.

Methods

Consecutive patients with NOE who underwent ¹⁸F-FDG PET at the end of antibiotic therapy and planar as well as single photon emission computed tomography-labeled leukocyte scintigraphy after completing the initial antibiotic treatment were retrospectively included. Semiquantitative analyses were performed to determine

SUBMITTER: Hurstel M 

PROVIDER: S-EPMC11487542 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature