Urinary metabolite concentrations of phthalate and plasticizers in infancy and childhood in the UNC baby connectome project.

ABSTRACT:

Introduction

Existing evidence suggests that exposure to phthalates is higher among younger age groups. However, limited knowledge exists on how phthalate exposure, as well as exposure to replacement plasticizers, di(isononyl) cyclohexane-1,2-dicarboxylate (DINCH) and di-2-ethylhexyl terephthalate (DEHTP), change from infancy through early childhood.

Methods

Urine samples were collected across the first 5 years of life from typically developing infants and young children enrolled between 2017 and 2020 in the longitudinal UNC Baby Connectome Project. From 438 urine samples among 187 participants, we quantified concentrations of monobutyl phthalate (MnBP), mono-3-carboxypropyl phthalate (MCPP), monoisobutyl phthalate (MiBP), monoethyl phthalate (MEP), monobenzyl phthalate (MBz

SUBMITTER: Thistle JE 

PROVIDER: S-EPMC11487613 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature