Real-world usage pattern, effectiveness and safety of oral tramadol/dexketoprofen trometamol fixed-dose combination in moderate-to-severe acute pain in Asia: a prospective, multicentre, observational study.

ABSTRACT:

Objectives

This study aims to determine the usage pattern, effectiveness and safety of oral tramadol 75 mg and dexketoprofen trometamol 25 mg fixed-dose combination (TRAM/DKP FDC) in the short-term treatment of moderate-to-severe acute pain in real-world clinical practice in Asia.

Design

Real-world, prospective, multicentre, observational, phase IV study.

Setting

13 tertiary-care hospital sites across the Philippines, Thailand, Malaysia and Singapore.

Participants

Adult patients aged 18-80 years prescribed TRAM/DKP FDC for the short-term (up to 5 days) treatment of moderate-to-severe acute pain.

Main outcome measures

Primary endpoints were the proportion of patients prescribed TRAM/DKP FDC with different types of postsurgical and non-surgical treatments,

SUBMITTER: Ho KY 

PROVIDER: S-EPMC11487850 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature