Biology and genetic diversity of <i>Candida krusei</i> isolates from fermented vegetables and clinical samples in China.

ABSTRACT: Candida krusei, also known as Pichia kudriavzevii, is an emerging non-albicans Candida (NAC) species causing both superficial and deep-seated infections in humans. This fungal pathogen is inherently resistant to the first-line antifungal drug, fluconazole, and is widely distributed in natural environments such as soil, foods, vegetables, and fruits. In this study, we collected 86 C. krusei strains from clinical settings and traditional fermented vegetables from different areas of China. Compared to C. krusei strains from fermented vegetables, clinical isolates exhibited a higher ability to undergo filamentation and biofilm development, which could facilitate its host colonization and infections. Isolates from fermented vegetables showed higher resistance

SUBMITTER: Zheng T 

PROVIDER: S-EPMC11487970 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature