Overcoming challenges in real-world evidence generation: An example from an Adult Medical Care Coordination program.

ABSTRACT: The Adult Medical Care Coordination program ("the program") was implemented at Mayo Clinic to promote patient self-management and improve 30-day unplanned readmission for patients with high risk for readmission after hospital discharge. This study aimed to evaluate the impact of the program compared to usual care using a pragmatic, stepped wedge cluster randomized trial ("stepped wedge trial"). However, several challenges arose including large differences between the study arms. Our goal is to describe the challenges and present lessons learned on how to overcome such challenges and generate evidence to support practice decisions. We describe the challenges encountered during the trial, the approach to addressing these challenges, and lessons learned for other learning health system resear

SUBMITTER: Savitz ST 

PROVIDER: S-EPMC11488116 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature