Advances in Raman spectroscopy for characterising oral cancer and oral potentially malignant disorders.

ABSTRACT: Oral cancer survival rates have seen little improvement over the past few decades. This is mainly due to late detection and a lack of reliable markers to predict disease progression in oral potentially malignant disorders (OPMDs). There is a need for highly specific and sensitive screening tools to enable early detection of malignant transformation. Biochemical alterations to tissues occur as an early response to pathological processes; manifesting as modifications to molecular structure, concentration or conformation. Raman spectroscopy is a powerful analytical technique that can probe these biochemical changes and can be exploited for the generation of novel disease-specific biomarkers. Therefore, Raman spectroscopy has the potential as an adjunct tool that can assist in the early diagno

SUBMITTER: Hanna K 

PROVIDER: S-EPMC11488342 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature