Clinical correlates of cerebellar injury in preterm infants with surgical necrotizing enterocolitis.

ABSTRACT:

Background

The preterm infants are at risk of cerebellar injury and the risk factors for necrotizing enterocolitis (NEC) associated cerebellar injury are not fully understood.

Aim

Determine the risk factors of cerebellar injury in infants with surgical necrotizing enterocolitis (NEC).

Methods

Retrospective study compared clinical/pathological information between surgical NEC infants with and those without cerebellar injury detected on brain MRI obtained at term equivalent age. Cerebellar Injury patterns that we identified on MRI brain were cerebellar hemorrhage, siderosis and/or cerebellar volume loss.

Results

Cerebellar injury (21/65, 32.3%) in preterm infants with NEC was associated with patent ductus arteriosus (PDA) (18/21(85.7%) vs. 25/44(56.8%); p = 0.021

SUBMITTER: Garg PM 

PROVIDER: S-EPMC11489020 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature