Physiological biodistribution on Ga68-PSMA PET/CT and the factors effecting biodistribution.

ABSTRACT:

Aim

The study aims to determine the physiological and pathophysiological distribution of the radiopharmaceutical (Ga⁶⁸-PSMA-617) and investigate whether there are differences in distribution according to the laboratory, histopathological and clinical findings that can affect image evaluation. Also, we aimed to determine cut-off values to distinguish physiological and pathological uptake in prostate, bone, and lymph nodes.

Materials and methods

229 prostate cancer patients who underwent Ga⁶⁸-PSMA PET/CT at our department were retrospectively analyzed. The patients were grouped according to PET/CT results, Gleason scores, PSA values, received treatments, metastatic status and other laboratory values. The SUV values of the organs, tissues, and pathological

SUBMITTER: Arcay Ozturk A 

PROVIDER: S-EPMC11489224 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature