Circulating levels of micronutrients and the risk of benign paroxysmal positional vertigo: A Mendelian randomization study.

ABSTRACT:

Background

Benign paroxysmal positional vertigo (BPPV) is a typical vestibular disease characterized by recurrent episodes of vertigo. The role of micronutrients in BPPV pathogenesis has not been extensively studied, prompting this investigation into the relationship between circulating micronutrients and BPPV risk. This research aimed to explore the relationship between blood micronutrient levels and BPPV risk via Mendelian randomization (MR) analysis, a robust method for inferring causality from observational data.

Methods

A total of 15 circulating micronutrients were assessed for their association with BPPV risk. MR analysis was conducted via the following methods: MR‒Egger, weighted median, simple model, inverse variance weighting (IVW), and weighted mode. Sensitivity an

SUBMITTER: Wang J 

PROVIDER: S-EPMC11489335 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature